Background: The perioperative period is a "vulnerable window" where surgical stress and anesthetic choice may influence long-term oncological prognosis. This review evaluates the impact of anesthetic

Background: Placenta accreta spectrum (PAS) is a life-threatening obstetric complication, and increasing prevalence of this condition underscores the importance of correct and prompt diagnosis to maxi

Background: Inappropriately prescribed antibiotics in pediatric outpatient care remain one of the most significant global drivers of antimicrobial resistance. Diagnostic uncertainty, excessive treatme

Objective: To evaluate the efficacy, safety, and clinical impact of blinatumomab across the treatment continuum of B-cell acute lymphoblastic leukemia. Design: Systematic evidence synthesis of randomi

Chlorhexidine is widely used in restorative dentistry because of its broad-spectrum antimicrobial activity, substantivity, and low cost. Beyond its antiseptic properties, chlorhexidine has attracted c

Introduction: Mild Cognitive Impairment (MCI) is regarded as an intermediate state between the normal cognitive decline associated with aging and more severe dementia. According to the diagnostic crit

Background: Urosepsis occurs in uncontrolled diabetes mellitus (DM) with a high morbidity because of changing beta-lactam resistance, which may become a problem in the empiric treatment and clinical o

Objective: To evaluate efficacy, durability, and safety of next-generation chimeric antigen receptor T-cell therapies in relapsed or refractory acute lymphoblastic leukemia. Design: A systematic revie

Background: Diabetic foot ulcers (DFUs) represent one of the most severe complications of diabetes mellitus and are caused by neuropathy, vascular insufficiency, and infection. Glycemic control as evi

Background: Focal thyroid incidentalomas (FTIs) found on 18F-FDG PET/CT (Fluorine-18-Fluorodeoxyglucose Positoin Emission Tomography/Computed Tomography) examinations are becoming commonplace in routi

Background: Prostate cancer is still a primary cause of male cancer morbidity and mortality. Multiparametric MRI (mpMRI), based on PI-RADS interpretation, has become invaluable in the diagnosis of cli

Objective: To review recent advancements in the understanding, diagnosis, and management of keratoconus, emphasizing the role of Scheimpflug imaging and the Belin ABCD classification in early detectio

Objective: To assess how renal function influences the efficacy and safety of Apixaban and Rivaroxaban in patients with atrial fibrillation (AF) and chronic kidney disease (CKD). Design: Systematic re

Background: Oestrogen and oestrogen-modulating therapies remain central to women’s health, yet their associations with cancer, cardiovascular outcomes, and fibroid disease continue to be debated. The

Background: Infantile Hypertrophic Pyloric Stenosis (IHPS) is the leading etiology of gastric outlet obstruction in infancy, with progressive pyloric musculature hypertrophy. A comprehensive compilati