Background: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy with survival rates approaching 90%. Hypertension is an increasingly recognized complication during induction che

Background: Stroke is a leading cause of death and disability worldwide, with disproportionately high mortality in sub-Saharan Africa. Data on the clinical characteristics and outcomes of critically i

Objective: To evaluate the clinical efficacy and translational relevance of Claudin-18.2 (CLDN18.2)–targeted therapy in advanced gastric and gastro-oesophageal junction adenocarcinoma, and to assess i

Objective: Fetal weight is an important indicator of pregnancy outcome and perinatal survival. Accurate estimation of fetal weight is important in the management of labour and care of the newborn, but

Background: The perioperative period is a "vulnerable window" where surgical stress and anesthetic choice may influence long-term oncological prognosis. This review evaluates the impact of anesthetic

Background: Antibiotic resistance is a major public health threat, causing high mortality and burdening healthcare systems, particularly in low-income countries. This study aimed to investigate bacter

Objective: To evaluate the efficacy, safety, and clinical impact of blinatumomab across the treatment continuum of B-cell acute lymphoblastic leukemia. Design: Systematic evidence synthesis of randomi

Objective: Emergency endotracheal intubation (ETI), a critical life-saving intervention in the emergency department (ED) is associated with significant complications and mortality. We aimed to evaluat

Objectives: This study aims to evaluate the prognostic value of pretreatment hematological and biochemical markers, including serum albumin, globulin, and alkaline phosphatase, on overall survival in

Background: Neonatal mortality and morbidity remain a persistent issue, particularly in low-resource settings. Kangaroo Mother Care (KMC), early and prolonged skin-to-skin contact with exclusive breas

Objective: To assess the prognostic value of the Sequential Organ Failure Assessment score in predicting maternal and neonatal outcomes among women with pregnancy-associated sepsis. Design: A prospect

Introduction: Ovarian metastases from gastrointestinal cancers (Krukenberg tumors) are rare, accounting for 1–2% of all ovarian malignancies. Despite their low incidence, they pose substaintial diagno

Posterior reversible encephalopathy syndrome (PRES) is a neurological condition that is identified by headache, seizures, vomiting and nausea as well as distorted vision and in many cases blindness. I

Objective: This study aimed to analyze the clinical causes, resuscitation interventions, and outcomes of pediatric cardiopulmonary arrest to identify key predictors of survival and neurological progno

Background: Pelvic fractures are among the most severe kinds of bone injuries, mostly associated with large morbidity and mortality, due to massive blood loss, associated abdominal injuries, and the c