Introduction: The scoring system of the hematopoietic cell transplantation comorbidity index (HCT-CI) was used in patients with Multiple Myeloma (MM) undergoing ASCT, and it could predict progress-fre

Objectives: This study aims to evaluate the prognostic value of pretreatment hematological and biochemical markers, including serum albumin, globulin, and alkaline phosphatase, on overall survival in

Background: The perioperative period is a "vulnerable window" where surgical stress and anesthetic choice may influence long-term oncological prognosis. This review evaluates the impact of anesthetic

Objective: To evaluate the efficacy, safety, and clinical impact of blinatumomab across the treatment continuum of B-cell acute lymphoblastic leukemia. Design: Systematic evidence synthesis of randomi

Introduction: Ovarian metastases from gastrointestinal cancers (Krukenberg tumors) are rare, accounting for 1–2% of all ovarian malignancies. Despite their low incidence, they pose substaintial diagno

Objective: This study aimed to analyze the clinical causes, resuscitation interventions, and outcomes of pediatric cardiopulmonary arrest to identify key predictors of survival and neurological progno

Objectives: To test the feasibility of hypofractionated irradiation using VMAT and IGRT in non-metastatic clinically pelvic nodes prostate cancer with evaluating toxicity and survival outcomes. Metho

Objective: To characterize post-immunotherapy lineage plasticity in pediatric B-cell acute lymphoblastic leukemia, including antigen escape, measurable residual disease failure, lineage switch, molecu

Background: Stroke is a leading cause of death and disability worldwide, with disproportionately high mortality in sub-Saharan Africa. Data on the clinical characteristics and outcomes of critically i

Background: Antibiotic resistance is a major public health threat, causing high mortality and burdening healthcare systems, particularly in low-income countries. This study aimed to investigate bacter

Background: Appropriate infant feeding influences child survival and development. This 2005-2006 study assessed maternal perceptions and reported practices in rural Agra and contextualised findings us

Background: Metabolic acidosis is a hallmark of physiological crisis in critical care, reflecting cellular hypoxia, renal insufficiency, or systemic metabolic failure. In regional tertiary centers, th

Background: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy with survival rates approaching 90%. Hypertension is an increasingly recognized complication during induction che

Objective: To evaluate the clinical efficacy and translational relevance of Claudin-18.2 (CLDN18.2)–targeted therapy in advanced gastric and gastro-oesophageal junction adenocarcinoma, and to assess i

Objective: Fetal weight is an important indicator of pregnancy outcome and perinatal survival. Accurate estimation of fetal weight is important in the management of labour and care of the newborn, but