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Systematic Review
Background: Focal thyroid incidentalomas (FTIs) found on 18F-FDG PET/CT (Fluorine-18-Fluorodeoxyglucose Positoin Emission Tomography/Computed Tomography) examinations are becoming commonplace in routi
Focal thyroid incidentalomas18F-FDG PET/CTmalignancy risksystematic reviewmeta-analysisrisk stratification
Original Article
Background: Coronary artery bypass grafting (CABG) is the standard surgical treatment for multi-vessel coronary artery disease (CAD). Although EuroSCORE remains the principal perioperative risk strati
Coronary artery bypass graftingHematological parametersMean platelet volumeHomocysteineNeutrophil-to-lymphocyte ratioPlatelet-to-lymphocyte ratio
Original Article
Background & Objectives: Early risk stratification is crucial in acute pancreatitis (AP) to improve clinical outcomes. This study evaluates the predictive accuracy of the PANC 3 score-a simple bedside
Acute PancreatitisPANC 3 ScoreCT Severity IndexTriageMortalityOrgan Failure.
Original Article
Background: Thyroid nodules are common clinical findings, with a small but significant proportion harboring malignancy. Fine- Needle Aspiration Cytology (FNAC) plays a pivotal role in the initial eval
Thyroid lesionsFNACBethesda SystemCytology.
Original Article
Acute pancreatitis is a leading emergency admission worldwide and is associated with substantial morbidity and mortality. Early risk stratification is critical to guiding therapeutic interventions. Th
Acute PancreatitisBISAPMorbidity
Original Article
Objective: To examine the correlation between serum Immunoglobulin E (IgE) levels and the clinical spectrum and severity of Cutaneous Adverse Drug Reactions (CADRs) in patients attending a tertiary ca
Cutaneous Adverse Drug Reactions (CADRs)Severe Cutaneous Adverse Reactions (SCARs)Serum Immunoglobulin E (IgE)Drug HypersensitivityStevens-Johnson Syndrome (SJS)/Toxic Epidermal Necrolysis (TEN)Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Review Article
Background: Retinoblastoma (RB) is the most common intraocular malignancy of childhood, with an excellent primary cure rate. However, survivors-particularly those with hereditary forms-face a heighten
Retinoblastomasecond primary cancermeta-analysisradiation therapyRB1 mutationheritable cancer
Original Article
Coronavirus disease (COVID-19) infection, can cause common cold symptoms to Acute Respiratory Distress syndrome, acute cardiac injury and multi-organ failure. Use of circulating biomarkers as the prog
BiomarkersCOVID-19Laboratory profileRisk stratificationSeverity
Original Article
Aims: Current screening paradigms for RA-associated lung disease lack validated serologic thresholds, while treatment remains guideline-agnostic with limited comparative effectiveness data. This prosp
Rheumatoid arthritisInterstitial lung diseaseUsual interstitial pneumoniaMycophenolate mofetilDisease Activity Score
Original Article
Objective: To evaluate first-trimester mean platelet volume as an early screening marker for predicting pre-eclampsia. Design: Prospective observational study. Subjects/Patients: 150 pregnant women wi
Antenatal CarePlatelet VolumePregnancy-Induced HypertensionPrenatal DiagnosisRisk AssessmentScreening.
Original Article
Background: Pregnancy-associated sepsis remains a significant contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. Early recognition is challenging due to
Sepsis Obstetric Scorepregnancy-associated sepsisICU admissionmaternal morbiditytriage tool.
Original Article
Background: Inguinal hernias are among the most frequent conditions encountered surgically worldwide. It is hypothesized that body mass index (BMI) is involved in the occurrence and distribution patte
inguinal herniabody mass indexdirect herniaindirect herniaretrospective studylogistic regression
Letter to the Editor
As an internal medicine specialist with a dedicated interest in insulin resistance, I have been engaged in ongoing clinical studies investigating various aspects of this complex condition. During rout
cardiovascular rsikheart rateinsulin resistance
Original Article
Background: Acute cholecystitis (AC) is a common surgical emergency with severity ranging from mild inflammation to life-threatening complications. Early severity assessment is essential for appropria
Acute cholecystitisNeutrophil-to-lymphocyte ratioDisease severityTokyo GuidelinesAAST classificationPrognostic biomarker.
Original Article
Background: Hemoperitoneum is a life-threatening surgical emergency requiring prompt anesthetic resuscitation and definitive hemorrhage control. However, evidence on perioperative anesthetic managemen
Anesthetic managementBlood transfusionEmergency surgeryHemoperitoneumPerioperative outcomesResource-limited settings.