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Case Series
Background: Multidrug-resistant (MDR) malaria has emerged as a critical challenge to malaria control and elimination efforts, particularly in endemic regions where artemisinin-based combination therap
Drug ResistanceMalariaInfectious Disease
Background: Thoracolumbar spine injuries constitute a major cause of trauma-related neurological disability worldwide, yet regional clinical data from low-resource settings remain limited. Objective:
Thoracolumbar fractureSpinal traumaNigeriaNeurological outcomeFrankel grade
Original Article
Background: Capecitabine–oxaliplatin (CAPOX) is a commonly used chemotherapy regimen in gastric and colorectal malignancies. Although its efficacy has been well established in randomized trials, real-
CAPOXgastric cancerrectal cancerchemotherapy toxicitytreatment compliance
Original Article
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common, dose-limiting toxicity of neurotoxic chemotherapy that significantly impairs quality of life (QoL) and functional status. Des
Chemotherapy-induced peripheral neuropathyCIPNtaxanesoxaliplatinbortezomibquality of life
Case Series
Introduction: Ovarian metastases from gastrointestinal cancers (Krukenberg tumors) are rare, accounting for 1–2% of all ovarian malignancies. Despite their low incidence, they pose substaintial diagno
ovarymetastatsisKrukenberg tumormolecular profilesurvival
Systematic Review
Background: Scabies, a parasitic skin infestation caused by Sarcoptes scabiei, remains a significant public health challenge globally, particularly in resource-limited settings and vulnerable populati
ScabiesSystematic ReviewMeta-AnalysisEpidemiologyDiagnosisTreatment
Systematic Review
Background: Rosacea is a chronic inflammatory dermatosis that is defined by recurrent facial erythema, papules, pustules, and telangiectasia. Even with growing world-wide acceptance, there are still s
RosaceaEpidemiologyRisk factorsPrevalenceSystematic ReviewMeta-analysis
Review Article
Background: Sleep bruxism involves involuntary grinding and clenching of teeth which is often under diagnosed. With appropriate diagnostic methods like polysomnography, clinical examinations and panor
Sleep bruxismtreatmentrevieweffectivenessoutcome
Review Article
Background: Root canal treatment is a boon in preserving teeth affected by apical odontitis. This procedure shows a fair success rate with lots of patients reporting alleviation of pain. However, the
Root canal treatmentFailureMeta analysesSystematic review
Original Article
Background: Antitubercular therapy-induced drug-induced liver injury (ATT-DILI) is an important adverse effect of tuberculosis treatment that may necessitate treatment interruption and adversely affec
TuberculosisAntitubercular therapyDrug-induced liver injuryHepatotoxicityRisk factorsTreatment outcomes.
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Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors (PCSK9i) are highly effective lipid-lowering agents that reduce low-density lipoprotein cholesterol (LDL-C) by enhancing LD
PCSK9PCSK9iLDL-CAlirocumabEvolocumabFamilial hypercholesterolaemia
Original Article
Background: Anemia is a frequent comorbidity in women with gynecological malignancies, adversely affecting tolerance to surgery, chemotherapy, and radiotherapy. Despite its clinical relevance, Indian
anemiagynecologic cancercervix carcinomaovarian cancerprevalence
Systematic Review
Background: Infantile Hypertrophic Pyloric Stenosis (IHPS) is the leading etiology of gastric outlet obstruction in infancy, with progressive pyloric musculature hypertrophy. A comprehensive compilati
Infantile hypertrophic pyloric stenosisEpidemiologyDiagnosisComplicationsGlobal healthInfant vomiting
Original Article
Introduction: Nimesulide-Paracetamol fixed-dose combination is widely used for managing acute painful conditions, yet real-world evidence remains limited. This study aimed to evaluate its effectivenes
Retrospective observational studyShort-term pain managementAnalgesic effectiveness
Original Article
Aims: Current screening paradigms for RA-associated lung disease lack validated serologic thresholds, while treatment remains guideline-agnostic with limited comparative effectiveness data. This prosp
Rheumatoid arthritisInterstitial lung diseaseUsual interstitial pneumoniaMycophenolate mofetilDisease Activity Score