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Original Article
Background
Septic shock remains a major cause of intensive care unit mortality despite advances in critical care management. Early identification of patients at high risk of adverse outcomes is essen
Septic ShockProcalcitoninMortalityBiomarkersLactateSOFA Score
Original Article
Background: Pregnancy-associated sepsis remains a significant contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. Early recognition is challenging due to
Sepsis Obstetric Scorepregnancy-associated sepsisICU admissionmaternal morbiditytriage tool.
Original Article
Background: Sepsis is a significant global health issue and a predominant cause of death in ICU patients. Traditionally, serum lactate and albumin have been utilized as prognostic biomarkers. However,
Sepsislactate-to-albumin ratio (LAR)ICU.
Review Article
Stroke is a leading cause of mortality and long-term disability worldwide, and a significant proportion of patients with severe acute stroke require intensive care and invasive mechanical ventilation
Functional Independence Intensive Care Units Mechanical Ventilation Prognostic Scores Stroke
Short Communication
Background: Esophageal carcinoma is frequently associated with severe malnutrition due to mechanical obstruction and systemic inflammation, which significantly impairs tolerance to chemoradiotherapy.
Esophageal CarcinomaEnteral NutritionPG-SGAChemoradiotherapyMalnutritionFeeding Jejunostomy
Images in Clinical Medicine
Background: Kaposi’s sarcoma is an HIV-associated vascular neoplasm that can cause significant morbidity through cutaneous, lymphatic, and soft tissue involvement. Case presentation: A 51-year-old HIV
Chronic lymphoedemaHand contracturesHIVAIDSKaposis sarcomaMusculoskeletal complicationsSoft tissue fibrosis
Review Article
Background: The perioperative period is a "vulnerable window" where surgical stress and anesthetic choice may influence long-term oncological prognosis. This review evaluates the impact of anesthetic
Breast cancer surgeryAnesthetic modalitiesOncological outcomesImmune modulation
Case Report
Objective: To describe a diagnostically challenging case of metastatic non-small cell lung carcinoma presenting as chronic pulmonary infection, resulting in prolonged diagnostic delay. Design: Single
Carcinoma Non-Small Cell LungDiagnostic ErrorsFluorodeoxyglucose F18Lung NeoplasmsPositron Emission Tomography Computed TomographyTuberculosis Pulmonary
Original Article
Background: Systemic Lupus Erythematosus (SLE) is a multifaceted autoimmune disease marked by chronic immune complex formation, leading to diverse clinical manifestations and multi-organ involvement.
Systemic Lupus ErythematosusProteinuriaGenderLupus NephritisRenal failure
Original Article
Objective: To determine the prevalence of metabolic syndrome and its individual components among patients with chronic obstructive pulmonary disease and to assess their association with disease severi
Chronic Obstructive Pulmonary DiseaseMetabolic SyndromeSystemic InflammationGlobal Initiative for Chronic Obstructive Lung Disease ClassificationCardiovascular Risk
Original Article
Background: Retinopathy of prematurity is a leading cause of preventable childhood blindness, primarily affecting preterm and low birth weight neonates. Aim: To determine the incidence of retinopathy
Retinopathy of prematurityPreterm neonatesLow birth weightRisk factors
Review Article
Background: Oestrogen and oestrogen-modulating therapies remain central to women’s health, yet their associations with cancer, cardiovascular outcomes, and fibroid disease continue to be debated. The
oestrogenhormone replacement therapybreast cancerovarian cancerendometrial canceruterine fibroids
Review Article
Pharmacovigilance is considered to be an essential part in ensuring drug safety across healthcare disciplines, despite that, its integration into dental practice is limited and overlooked. Dentists pr
PharmacovigilanceAdverse drug reactionsPharmacist-dentist collaborationDigital reporting toolPatient education
Original Article
Objective: To examine the correlation between serum Immunoglobulin E (IgE) levels and the clinical spectrum and severity of Cutaneous Adverse Drug Reactions (CADRs) in patients attending a tertiary ca
Cutaneous Adverse Drug Reactions (CADRs)Severe Cutaneous Adverse Reactions (SCARs)Serum Immunoglobulin E (IgE)Drug HypersensitivityStevens-Johnson Syndrome (SJS)/Toxic Epidermal Necrolysis (TEN)Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Original Article
Background: Platelet volume indices (PVI) such as mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT) have been implicated in the pathogenesis and prognosis of acute
Acute coronary syndromemean platelet volumeplatelet distribution widthplateletcritmyocardial infarctionSTEMI