Background: The worldwide prevalence of obesity has reached an epidemic level and has presented a significant burden to public health infrastructure. There is a critical need for novel predictive inst

Background: Timely liberation from invasive mechanical ventilation remains a major challenge in critically ill patients. Although the Rapid Shallow Breathing Index (RSBI) is widely used to assess extu

Protein tyrosine phosphatase 1B (PTP1B) is an important therapeutic target for developing novel antihyperglycemic agents. Tricyclic terpenoid derivatives represent promising scaffolds for PTP1B inhibi

Background: Acute pancreatitis (AP) is a common inflammatory condition with variable severity, ranging from mild self-limiting disease to severe forms with significant morbidity and mortality. Early p

Objectives: The objective of the study was to use machine learning (ML) methodology to create prediction models for hypertension based on nationally representative health and demographic surveillance

Objective: The objective of this study was to evaluate the role of C-reactive protein (CRP) in early prediction of anastomotic leak and temporal relationship of its levels with clinical manifestation

Background: Induction of labour requires reliable prediction of delivery outcome. Ultrasonographic cervical parameters, particularly cervical length, may objectively complement the subjective Bishop s

Objective: To evaluate cervicovaginal beta-human chorionic gonadotropin as a predictor of spontaneous preterm birth and its association with cervical length and Bishop score. Design: Prospective obser

Background: Cervical spine surgery outcomes in resource‑constrained settings are often assessed subjectively, lacking standardised objective measures that account for local realities. This study aimed

Background: Several studies have assessed liver and kidney functions in patients with coronary artery disease (CAD). However, the association of liver and kidney function markers with CAD remains uncl

Objective: To evaluate first-trimester mean platelet volume as an early screening marker for predicting pre-eclampsia. Design: Prospective observational study. Subjects/Patients: 150 pregnant women wi

Background Septic shock remains a major cause of intensive care unit mortality despite advances in critical care management. Early identification of patients at high risk of adverse outcomes is essen

Background: Esophageal varices are a major complication of portal hypertension in liver cirrhosis and are associated with significant morbidity and mortality. Although upper gastrointestinal endoscopy

Background: Pregnancy-associated sepsis remains a significant contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. Early recognition is challenging due to

Background: Sepsis is a significant global health issue and a predominant cause of death in ICU patients. Traditionally, serum lactate and albumin have been utilized as prognostic biomarkers. However,