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Humans spend a great deal of time sleeping and dreaming. While the benefits of good sleep hygiene are well-known, fewer appreciate the importance of dreaming. This paper investigates the necessity of
REM sleep deprivationMemoryLong-TermEmotional RegulationNicotineAntidepressive Agents
Original Article
Background: The comparative effectiveness of Catheter Flow Control Valves (CFCV) versus Conventional Continuous Flow Catheters (CFC) remains understudied in outpatient settings. This research evaluate
Catheter Flow Control ValveContinuous Flow Catheterurinary catheterpatient satisfactionoutpatient careurinary tract infections
Case Series
The agenesis of maxillary lateral incisors is a common dental anomaly that often presents aesthetic and functional challenges for patients and orthodontists. Patients are generally faced with two main
agenesismaxillary lateral incisorspace closurecanine substitutionprosthetic replacementmultidisciplinary approach
Review Article
Background: Retinoblastoma (RB) is the most common intraocular malignancy of childhood, with an excellent primary cure rate. However, survivors-particularly those with hereditary forms-face a heighten
Retinoblastomasecond primary cancermeta-analysisradiation therapyRB1 mutationheritable cancer
Original Article
Background: Buccal mucosal graft urethroplasty (BMGU) is now the gold standard in the treatment of anterior urethral strictures, particularly of long lengths or recurrences. But heterogeneity of outco
Buccal mucosal graftUrethroplastyAnterior urethral strictureRecurrenceGlobal outcomesPROMs
Review Article
Background: Glycated haemoglobin (HbA1c) is considered the gold-standard biomarker for assessing long-term glycaemic control and is widely used in the diagnosis and monitoring of diabetes mellitus. Ho
Glycated albuminGlycated haemoglobinHbA1cDiabetes mellitusGlycaemic controlChronic kidney disease
Original Article
Background: Foot involvement is a common but often overlooked manifestation of rheumatoid arthritis (RA) that contributes to pain, deformity, impaired mobility, and reduced quality of life. Since the
Rheumatoid arthritisFoot involvementMetatarsophalangeal jointUltrasonographyFoot Function Index.
Original Article
Background: Pharmacological treatment of chronic obstructive pulmonary disease (COPD) is well established, yet a sizeable minority of patients continue to deteriorate and die during acute exacerbation
COPDacute exacerbationmedication adherenceMMAS-8in-hospital mortalityCRP-to-albumin ratio
Original Article
Objective: To evaluate the progression of tricuspid regurgitation (TR) and associated echocardiographic parameters following isolated mitral valve surgery, and to identify preoperative predictors of T
tricuspid valve insufficiencymitral valve surgerypulmonary hypertensiontricuspid annular dilatationright ventricular functionTAPSE
Review Article
Stroke is a leading cause of mortality and long-term disability worldwide, and a significant proportion of patients with severe acute stroke require intensive care and invasive mechanical ventilation
Functional Independence Intensive Care Units Mechanical Ventilation Prognostic Scores Stroke
Review Article
Background: The perioperative period is a "vulnerable window" where surgical stress and anesthetic choice may influence long-term oncological prognosis. This review evaluates the impact of anesthetic
Breast cancer surgeryAnesthetic modalitiesOncological outcomesImmune modulation
Systematic Review
Objective: To evaluate the efficacy, safety, and clinical impact of blinatumomab across the treatment continuum of B-cell acute lymphoblastic leukemia. Design: Systematic evidence synthesis of randomi
Acute Lymphoblastic LeukemiaBlinatumomabImmunotherapyMinimal Residual DiseaseSurvival Analysis
Review Article
Chlorhexidine is widely used in restorative dentistry because of its broad-spectrum antimicrobial activity, substantivity, and low cost. Beyond its antiseptic properties, chlorhexidine has attracted c
ChlorhexidineRestorative DentistryDentin BondingMatrix MetalloproteinasesCytotoxicityDrug Utilization
Original Article
Background: The study compares the post-operative restoration of hearing in patients undergoing Tympanoplasty for chronic otitis media, specifically between the use of Cartilage Graft and Temporalis F
Cartilage TympanoplastyChronic otitis mediaTemporalis Fascia Graft Techniques
Systematic Review
Type 2 diabetes mellitus (T2DM) is a significant contributor to morbidity and mortality globally and more than 500 million people are already affected. It has been estimated that almost 800 million ma
Antibiotics exposureType 2 diabetes mellitusMeta-analysis.