Objective: To characterize post-immunotherapy lineage plasticity in pediatric B-cell acute lymphoblastic leukemia, including antigen escape, measurable residual disease failure, lineage switch, molecu

Objective: To evaluate efficacy, durability, and safety of next-generation chimeric antigen receptor T-cell therapies in relapsed or refractory acute lymphoblastic leukemia. Design: A systematic revie

Surgical resection remains the cornerstone of curative treatment for solid tumors. However, the same biological processes that the body mobilizes to heal the surgical wound may paradoxically favor the

Objective: To evaluate the efficacy, safety, and clinical impact of blinatumomab across the treatment continuum of B-cell acute lymphoblastic leukemia. Design: Systematic evidence synthesis of randomi