Objective: To evaluate the clinical efficacy and translational relevance of Claudin-18.2 (CLDN18.2)–targeted therapy in advanced gastric and gastro-oesophageal junction adenocarcinoma, and to assess i

Background: Acute cholecystitis (AC) is a common surgical emergency with severity ranging from mild inflammation to life-threatening complications. Early severity assessment is essential for appropria

Background: Glycated haemoglobin (HbA1c) is considered the gold-standard biomarker for assessing long-term glycaemic control and is widely used in the diagnosis and monitoring of diabetes mellitus. Ho

Background: Oxidative stress plays a crucial role in the complications associated with chronic kidney disease (CKD), particularly in individuals undergoing dialysis. Malondialdehyde (MDA), a key marke

Objective: To examine the correlation between serum Immunoglobulin E (IgE) levels and the clinical spectrum and severity of Cutaneous Adverse Drug Reactions (CADRs) in patients attending a tertiary ca

Objective: The effect of Cardiopulmonary bypass on serum Procalcitonin, and its correlation with other markers of inflammation in paediatric cardiac surgery patients. Design: A prospective observation

Objective: To evaluate associations between environmental and occupational exposures and acquired aplastic anemia, assess dose–response relations, and integrate mechanistic evidence. Design: Systemati

Background: Stress hyperglycemia and magnesium disturbances are common in critically ill patients and have been associated with adverse clinical outcomes. The glycemic gap, which reflects acute hyperg

Background Septic shock remains a major cause of intensive care unit mortality despite advances in critical care management. Early identification of patients at high risk of adverse outcomes is essen

Introduction: Sepsis-3 remains a leading cause of ICU mortality. In resource-limited settings, there is a critical need for inexpensive, rapid biomarkers for risk stratification. This study evaluated

Background: Sepsis is a significant global health issue and a predominant cause of death in ICU patients. Traditionally, serum lactate and albumin have been utilized as prognostic biomarkers. However,

Background: Placenta accreta spectrum (PAS) is a life-threatening obstetric complication, and increasing prevalence of this condition underscores the importance of correct and prompt diagnosis to maxi

Introduction: The management of HF has evolved significantly with the introduction of novel therapeutic agents and biomarker-guided strategies. NT-proBNP (N-terminal pro-B-type natriuretic peptide) gu

Objective: To evaluate the correlation between serum CA-125 levels and histopathological findings in ovarian tumors. Design: Prospective descriptive study. Subjects/Patients: A total of 59 patients wi

Background: To assess whether cervicovaginal β-human chorionic gonadotropin (β-HCG) and cervical length (CL) by transvaginal sonography predict spontaneous preterm delivery. Methods: In this prospecti