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Original Article
Background: Transport of critically ill patients is associated with potentially serious clinical and technical adverse events. However, limited data exists on transport safety in the Democratic Republ
Critical careDemocratic Republic of the CongoPatient safetyPatient transport : Transport-related adverse events.
Original Article
Background: Hemoperitoneum is a life-threatening surgical emergency requiring prompt anesthetic resuscitation and definitive hemorrhage control. However, evidence on perioperative anesthetic managemen
Anesthetic managementBlood transfusionEmergency surgeryHemoperitoneumPerioperative outcomesResource-limited settings.
Original Article
Background: Coronary artery bypass grafting (CABG) is the standard surgical treatment for multi-vessel coronary artery disease (CAD). Although EuroSCORE remains the principal perioperative risk strati
Coronary artery bypass graftingHematological parametersMean platelet volumeHomocysteineNeutrophil-to-lymphocyte ratioPlatelet-to-lymphocyte ratio
Original Article
Introduction: Gastrointestinal (GI) endoscopy is essential for managing various GI conditions, particularly in critically ill patients. These procedures, often performed under anaesthesia, carry risks
EndoscopyGastrointestinalAnaesthesiaConscious SedationAdverse EventsRisk Assessment
Original Article
Background: Prostate cancer is a leading malignancy among men worldwide, yet real-world treatment outcome data from low-resource oncology settings remain limited. Goserelin-based androgen deprivation
Prostate cancergoserelinandrogen deprivation therapyprostate-specific antigenbiochemical recurrenceSudan.
Original Article
Objective: To evaluate admission blood glucose levels as a predictor of in-hospital major adverse cardiovascular events (MACE) in non-diabetic patients with Acute Coronary Syndrome (ACS). Design: Pros
Hyperglycemiacardiogenic shockarrhythmiaejection fractionreliable.
Systematic Review
Objective: To evaluate the efficacy, safety, and clinical impact of blinatumomab across the treatment continuum of B-cell acute lymphoblastic leukemia. Design: Systematic evidence synthesis of randomi
Acute Lymphoblastic LeukemiaBlinatumomabImmunotherapyMinimal Residual DiseaseSurvival Analysis
Original Article
Background: Capecitabine–oxaliplatin (CAPOX) is a commonly used chemotherapy regimen in gastric and colorectal malignancies. Although its efficacy has been well established in randomized trials, real-
CAPOXgastric cancerrectal cancerchemotherapy toxicitytreatment compliance
Original Article
Objective: To evaluate the efficacy and safety of vitamin D₃ supplementation in vitamin D-deficient Indian adults. Design: Retrospective, multi-center, observational study. Methods: Medical records of
CholecalciferolReal World EvidenceSerum vitamin D levelVitamin D deficiency
Original Article
Objective: To assess the clinical effectiveness and safety of Co-Amoxiclav in the real-world treatment of dental infections. Design: Multicenter, retrospective, real world evidence study. Subjects: 4,
Amoxicillin/clavulanic acidantimicrobial resistancedental carieseffectivenessodontogenic infectionssafety
Original Article
Introduction: Laparoscopic cholecystectomy, the gold standard for treating gallbladder diseases, requires reliable closure of the cystic duct and artery, typically using titanium ligating clips. This
Bile leakageLaparoscopic cholecystectomyLigaclip® ligating clipsPostoperative outcomesTrutie® ligating clips
Original Article
Objective: To evaluate the effectiveness and safety of cefixime for managing typhoid fever among Indian patients. Design: Multicenter, single-arm retrospective study. Patients: Patients with typhoid f
CefiximeRetrospectiveTyphoid feverThird generation cephalosporins
Original Article
Objective: To assess the real-world effectiveness and safety of vitamin D3 supplementation in children. Design: A retrospective, multicentre, observational real-world evidence study. Subjects/Patients
CholecalciferolPediatric healthSerum vitamin D levelVitamin D deficiency
Original Article
Background: Although statins remain the cornerstone of lipid-lowering therapy, LDL-C targets are often not achieved with statin monotherapy. This study evaluated the effectiveness and tolerability of
Dyslipidemialow-density lipoprotein cholesterolrosuvastatinezetimibecombination therapyatherosclerotic cardiovascular disease.
Original Article
Objective: To evaluate the effect of a structured awareness training program on the knowledge, attitude, and practices of Auxiliary Nurse Midwife (ANM) students regarding vaccine vigilance and Adverse
EducationInservice TrainingNurse MidwivesPharmacovigilanceVaccines effects