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Systematic Review
Objective: To evaluate the efficacy, safety, and clinical impact of blinatumomab across the treatment continuum of B-cell acute lymphoblastic leukemia. Design: Systematic evidence synthesis of randomi
Acute Lymphoblastic LeukemiaBlinatumomabImmunotherapyMinimal Residual DiseaseSurvival Analysis
Original Article
Objective: To evaluate the effect of a structured awareness training program on the knowledge, attitude, and practices of Auxiliary Nurse Midwife (ANM) students regarding vaccine vigilance and Adverse
EducationInservice TrainingNurse MidwivesPharmacovigilanceVaccines effects
Original Article
Background: Capecitabine–oxaliplatin (CAPOX) is a commonly used chemotherapy regimen in gastric and colorectal malignancies. Although its efficacy has been well established in randomized trials, real-
CAPOXgastric cancerrectal cancerchemotherapy toxicitytreatment compliance
Original Article
Objective: The aim of this study is to identify the rate of major and minor disagreements with diagnoses from external institutions for patients with head and neck lesions or clinical contexts. Design
Surgical pathologyPursuing a second opinion surgical pathologySurgical pathology on continuum of treatmentHead and neck lesionsDiagnostic errors
Original Article
Objective: To evaluate the efficacy and safety of vitamin D₃ supplementation in vitamin D-deficient Indian adults. Design: Retrospective, multi-center, observational study. Methods: Medical records of
CholecalciferolReal World EvidenceSerum vitamin D levelVitamin D deficiency
Original Article
Introduction: Nimesulide-Paracetamol fixed-dose combination is widely used for managing acute painful conditions, yet real-world evidence remains limited. This study aimed to evaluate its effectivenes
Retrospective observational studyShort-term pain managementAnalgesic effectiveness
Original Article
Objective: To evaluate the effectiveness and safety of cefixime for managing typhoid fever among Indian patients. Design: Multicenter, single-arm retrospective study. Patients: Patients with typhoid f
CefiximeRetrospectiveTyphoid feverThird generation cephalosporins
Original Article
Introduction: Gastrointestinal (GI) endoscopy is essential for managing various GI conditions, particularly in critically ill patients. These procedures, often performed under anaesthesia, carry risks
EndoscopyGastrointestinalAnaesthesiaConscious SedationAdverse EventsRisk Assessment
Original Article
Objective: To assess the clinical effectiveness and safety of Co-Amoxiclav in the real-world treatment of dental infections. Design: Multicenter, retrospective, real world evidence study. Subjects: 4,
Amoxicillin/clavulanic acidantimicrobial resistancedental carieseffectivenessodontogenic infectionssafety
Original Article
Objective: To assess the real-world effectiveness and safety of vitamin D3 supplementation in children. Design: A retrospective, multicentre, observational real-world evidence study. Subjects/Patients
CholecalciferolPediatric healthSerum vitamin D levelVitamin D deficiency
Original Article
Introduction: Laparoscopic cholecystectomy, the gold standard for treating gallbladder diseases, requires reliable closure of the cystic duct and artery, typically using titanium ligating clips. This
Bile leakageLaparoscopic cholecystectomyLigaclip® ligating clipsPostoperative outcomesTrutie® ligating clips
Original Article
Objective: This study aimed to evaluate the safety and efficacy of Sovateltide in patients diagnosed with acute ischemic stroke beyond the thrombolysis eligibility period. Methods: We conducted a pros
Sovateltideischemic strokeneuroprotectionthrombolysistubercular meningitis